Characterization and anti-inflammatory study of Solamargin extracted from of Solanum xanthocarpum

Abstract

Solanum xanthocarpum is also called from different name in various different languages in India. The Solanum xanthocarpum is a very prickly diffused bright-green, perennial herb of the family Solanaceae. It active constituents Solamargin reported Ayurvedic system of medicine has been found to have anti-asthematic, hypoglycemic, hepatoprotective, anti-inflammatory, antipyretic and nephron-protective activities. Inflammation is a complex response to local injury or other trauma; it is characterized by redness, heat, swelling, and pain. Inflammation is a normal protective response to tissue injury caused by physical trauma, noxious chemical and/or microbial agents. Inflammation is the body response towards foreign substances such as pathogens, allergens, chemical irritants as well as injury which involves infiltration of leukocytes and generation of pro-inflammation factors to the injured site. Major compounds co-eluted at 40% acetonitrile as a white-powder and were separated using preparative TLC to afford compound of steroidal alkaloid.